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Genetic mapping reveals how cancer grows

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Scientists all over the world have been trying to understand cancer, which is one of the deadliest diseases in the world, for many years.

Researchers have been trying to figure out where cancer comes from and what early treatments can help counter this illness.

Now, researchers have created a map of the prostrate which shows healthy areas and those that contain cancerous cells.

Experts from the Karolinska Institutet, Solna, Sweden, the University of Oxford, and KTH Royal Institute of Technology, Science for Life Laboratory discovered that prostrate tumours have an unknown range of genetic variation.

The team saw what genetic changes take place in the tissue using spatial transcriptomics. Their work can play an immense role in improving early cancer diagnosis.

The study published in the journal Nature said that this technique was better because the older ones take samples from cancerous areas and study the DNA of cells with tumours only. Researchers said that prostrate cancer and others like it are three-dimensional and any one sample should hint toward a tumour.

The lead of the study, Alastair Lamb, said that they were “fairly sure” cancer started with genetic mutations. Lamb said that this amount of clarity was never there before.

To the surprise of the scientists, genetic characteristics of cancer were seen in healthy tissues too. 

In their vast study, researchers scrutinised 150,000 regions in two breast cancers, a lymph node, some skin, some brain tissue, and three prostrates to develop an algorithm that could track cells with similar genetic characteristics.

“Mapping thousands of tissue regions in a single experiment is an unprecedented approach to deconvolute the heterogeneity of tumours and their microenvironment,” said Professor Joakim Lundeberg of KTH Royal Institute of Technology.

He said that high-resolution views can change the way we look at the cancer ecosystem. 

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Bitcoin makes its first breach of $94,000.

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As news broke that Donald Trump’s social media company was in negotiations to acquire cryptocurrency trading platform Bakkt (BKKT.N), Bitcoin surged to a record high above $94,000, adding to optimism that the next Trump administration would be cryptocurrency-friendly.

This year, Bitcoin, the largest and most well-known cryptocurrency in the world, has more than doubled in value. Just before the close of the previous session, it reached a record high of $94,078 before closing at $92,104 in Asian hours on Wednesday.

According to the Financial Times, which cited two persons with knowledge, NYSE-owner Intercontinental Exchange (ICE.N) is supporting Trump Media and Technology Group (DJT.O), opens new tab, which runs Truth Social, in its pursuit of an all-stock purchase of Bakkt.

In addition to traders taking advantage of the first day of options trading on the Nasdaq over BlackRock’s Bitcoin ETF (IBIT.O), Tony Sycamore, market analyst at IG, stated that the Trump deal chatter had helped push bitcoin to a record high.

As traders hoped that President-elect Trump’s pledged support for digital assets would result in a less stringent regulatory framework and give bitcoin a boost after a sluggish few months, cryptocurrencies have surged since the U.S. election on November 5.

According to data and analytics aggregator CoinGecko, the global cryptocurrency market is now worth over $3 trillion, a new high, due to the growing excitement.

Australian online broker Pepperstone’s head of research, Chris Weston, stated that there is genuine underlying purchasing pressure on bitcoin and that “another kick higher should bring in a fresh chase from those who like to buy what’s strong.”

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The PTA discloses how many VPNs are registered in Pakistan.

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Speaking at the Senate Standing Committee on IT meeting in Islamabad, which was presided over by Palwasha Khan, was the PTA chief.

The continuous regulation of Virtual Private Networks (VPNs) in Pakistan was the main topic of discussion. The committee called for the next meeting and voiced concerns about the Minister of State for IT’s absence for the third consecutive session.

“We have spent the last two years developing VPN legislation. Uninterrupted internet connection is guaranteed by registered VPNs without sacrificing privacy, according to the PTA chairman.

During the session, Senator Muhammad Humayun criticized the measures, saying, “Shutting down platforms like X (formerly Twitter) is jeopardizing the entire IT industry and impacting the livelihoods of over 2.5 million individuals in Pakistan.”

He opposed laws that would hurt independent contractors and small companies.

Although the PTA promised that registered VPNs would not experience internet outages, committee members wanted to know the exact legal foundation for these regulations. Senator Kamran Murtaza asked for documents that detailed the requirements for registration.

“If VPN services are abruptly halted, there will be a major backlash,” Senator Afnan Ullah said. While pointing out that Pakistan’s IT exports had increased by 20% in the previous year, he emphasised that the sector was still lagging behind India.

Concerns over the viability of the existing VPN whitelist method were voiced by the committee. While IT officials admitted that more than 1 million freelancers in Pakistan rely significantly on VPNs for their business, Senator Humayun pointed out that the laws should be more beneficial than harmful.

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Pakistan declares AI chatbots to be dangers to security.

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The National Computer Emergency Response Team (CERT) has released a security advisory concerning the increasing utilization of artificial intelligence (AI) chatbots, emphasizing potential hazards related to the exposing of private data.

The recommendation recognizes that AI chatbots, like ChatGPT, have gained significant popularity for personal and professional duties owing to their capacity to improve productivity and engagement. Nonetheless, the CERT cautions that these AI systems frequently retain sensitive information, so posing a danger of data breaches.

Engagements with AI chatbots may encompass sensitive information, such as corporate strategy, personal dialogues, or confidential correspondence, which could be compromised if inadequately safeguarded. The warning emphasizes the necessity for a comprehensive cybersecurity framework to alleviate concerns associated with AI chatbot utilization.

Users are advised against inputting critical information into AI chatbots and are encouraged to deactivate any chat-saving functionalities to mitigate the danger of unwanted data access. The CERT additionally advises performing routine system security checks and employing monitoring tools to identify any anomalous behavior from AI chatbots.

Organizations are urged to adopt rigorous security protocols to safeguard against possible data breaches resulting from AI-driven interactions.

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